Dock2 Antibody | EMD Millipore 09-454 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Dock2 Antibody

catalog :

09-454

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, western blot knockout validation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; loading ...; fig s4	Ushijima M, Uruno T, Nishikimi A, Sanematsu F, Kamikaseda Y, Kunimura K, et al. The Rac Activator DOCK2 Mediates Plasma Cell Differentiation and IgG Antibody Production. Front Immunol. 2018;9:243 pubmed publisher
	Guo X, Li F, Xu Z, Yin A, Yin H, Li C, et al. DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure. J Lipid Res. 2017;58:1777-1784 pubmed publisher

product information

Catalog Number :

09-454

Subcategory :

Cell Structure

Product Name :

Anti-Dock2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q8C3J5

Host Name :

Rabbit

Antigen :

Dock2

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-Dock2 Antibody

Cross Reactivity :

Human;Mouse;Horse;Primate

Background :

Dock2 (Dedicator of cytokinesis 2), is a large protein involved in intracellular signaling networks and a member of the DOCK-A subfamily which function as activators of small G proteins. Dock2 specifically activates isoforms of the small G protein Rac and appears to be expressed specifically in leukocytes. These cells express both Rac1 and Rac2 and Dock2 has been shown to bind and promote nucleotide exchange on both of these isoforms. (Nishihara, 1999)

ALT Names :

dedicator of cyto-kinesis 2;dedicator of cytokinesis 2

Immunogen :

KLH-conjugated synthetic peptide near amino acid 1730, within the internal region of mouse DOCK2.

Specificity :

09-454 recognizes mouse DOCK2.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Maintain at 2-8°C for up to 1 year from date of receipt.