Ras Antibody, H Palmitoylated | EMD Millipore 09-187 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Ras Antibody, H Palmitoylated

catalog :

09-187

quantity :

100 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot

product information

Catalog Number :

09-187

Subcategory :

Cell Signaling

Product Name :

Anti-Ras Antibody, H Palmitoylated

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P01111

Host Name :

Rabbit

Antigen :

Ras

Conjugate :

Affinity Purified

Product Description :

Anti-Ras Antibody, H Palmitoylated

Cross Reactivity :

Human;Mouse;Rat;Chicken

Background :

Ras proteins function as GDP/GTP-regulated binary switches in signal transduction cascades that can lead to cell growth, proliferation, differentiation, or survival. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. This Ras superfamily has at least five major branches that include Ras, Rho, Ran, Arf/Sar, Rab. Ras itself has 3 primary isoforms (H-Ras, N-Ras, and K-Ras) that differ in their approximately 20 C-terminal amino acids. They are collectively referred to as Ras. In its active form, Ras is bound to GTP. This causes a conformational change that allow it to interact and bind to several effector molecules, most notably the members of the Raf family, the RalGDS family, and Phosphoinositide 3-kinases (PI3 Kinase). Ras then cleaves GTP to GDP resulting in its inactivation. In its oncogenic, mutated state, Ras is unable to hydrolyze GTP to GDP, thus staying in an active state and activating numerous pathways.

ALT Names :

N-ras protein part 4;Transforming protein N-Ras ;neuroblastoma RAS viral (v-ras) oncogene homolog ;v-ras neuroblastoma RAS viral oncogene homolog

Immunogen :

KLH-conjugated synthetic linear peptide corresponding to the hypervariable region of Ras, H, palmitoylated.

Specificity :

This antibody detects the hypervariable region Ras, H Palmitoylated.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.