G9a (BAT8) Antibody | EMD Millipore 09-071 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

G9a (BAT8) Antibody

catalog :

09-071

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1e	Park S, Yi H, Suh N, Park Y, Koh J, Jeong S, et al. Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-?B. Oncotarget. 2016;7:39796-39808 pubmed publisher

product information

Catalog Number :

09-071

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-G9a (BAT8) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96KQ7

Host Name :

Rabbit

Antigen :

G9a (BAT8)

Conjugate :

Affinity Purified

Product Description :

Anti-G9a (BAT8) Antibody

Cross Reactivity :

Human;Mouse;Rat;Canine

Background :

G9a (BAT8 or Histone-lysine N-methyltransferase) is thought to be involved in intracellular protein-protein interaction and is a lysine-preferring histone methyltransferase. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. The presence of the ankyrin repeats also suggests that G9a is involved in intracellular protein-protein interaction. Like Suv39h1, G9a transfers methyl groups to the lysine residues of histone H3, but with a 10- to 20-fold higher activity. G9a is localized to the nucleus but not in the repressive chromatin domains of centromeric loci, in which Suv39h1 family proteins were localized. This protein is probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. G9a also methylates histone H1.

ALT Names :

G9A histone methyltransferase ;H3-K9-HMTase 3 ;HLA-B associated transcript 8;HLA-B-associated transcript 8;Histone H3-K9 methyltransferase 3;Lysine N-methyltransferase 1C ;Protein G9a ;ankyrin repeat-containing protein ;chromosome 6 open reading frame 30 ;euchromatic histone-lysine N-methyltransferase 2

Immunogen :

KLH-conjugated linear peptide corresponding to G9a (BAT8).

Specificity :

This antibody recognizes G9a (BAT8).

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable at 2-8°C for 1 year from date of receipt.