Histone H2A.Z Antibody | EMD Millipore 07-718 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H2A.Z Antibody

catalog :

07-718

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Saccharomyces cerevisiae S288C

application :

western blot

product information

Catalog Number :

07-718

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H2A.Z Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q12692

Host Name :

Rabbit

Antigen :

Histone H2A.Z

Conjugate :

Affinity Purified

Product Description :

Anti-Histone H2A.Z Antibody

Cross Reactivity :

Yeast

Background :

H2A.Z, also known as H2AFZ, is a variant of histone H2A variant that is highly conserved from yeast to humans. Like other histone variants, H2A.Z is encoded by a unique gene, resulting in a slightly divergent type of H2A with specialized functions. H2A.Z is involved in chromatin compaction by stabilizing the histone octamer within the nucleosome. It promotes gene expression through the creation of an open domain of chromatin that is more easily transcribed. H2A.Z is nonrandomly distributed throughout the genome, targeted primarily to pericentric heterochromatin, but excluded from the inactive X chromosome and the nucleolus. H2A.Z is associated with both euchromatin and facultative heterochromatin. DNA methylation can influence chromatin structure and effect gene silencing by excluding H2A.Z, and likewise, H2A.Z protects genes from DNA methylation. Thus, H2A.Z plays a role in regulating heterochromatin silencing and is involved in transcriptional control.

ALT Names :

H2AZ, HTA3, H2AZ;Htz1

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of yeast Histone H2A.Z.

Specificity :

This antibody recognizes the C-terminus of Histone H2A.Z.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt