Histone H3 Antibody, CT, pan | EMD Millipore 07-690 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3 Antibody, CT, pan

catalog :

07-690

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation, chromatin immunoprecipitation, ChIP-Seq

citations: 16

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; human; fig 4f	Lu F, Wiedmer A, Martin K, Wickramasinghe P, Kossenkov A, Lieberman P. Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus. J Virol. 2017;91: pubmed publisher
western blot; human; loading ...; fig 2d	Utani K, Fu H, Jang S, Marks A, Smith O, Zhang Y, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability. Nucleic Acids Res. 2017;45:7807-7824 pubmed publisher
ChIP-Seq; mouse; loading ...; fig 3a	Endoh M, Endo T, Shinga J, Hayashi K, Farcas A, Ma K, et al. PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. elife. 2017;6: pubmed publisher
western blot; human; loading ...; fig s5b	Murai J, Feng Y, Yu G, Ru Y, Tang S, Shen Y, et al. Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition. Oncotarget. 2016;7:76534-76550 pubmed publisher
western blot; human; fig 2	García Carpizo V, Sarmentero J, Han B, Grana O, Ruiz Llorente S, Pisano D, et al. NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation. Sci Rep. 2016;6:32952 pubmed publisher
western blot; human; loading ...; fig 5d	Kunze M, Benz F, Brauß T, Lampe S, Weigand J, Braun J, et al. sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism. Biochim Biophys Acta. 2016;1859:848-59 pubmed publisher
chromatin immunoprecipitation; human; fig 1	Dheekollu J, Wiedmer A, Sentana Lledo D, Cassel J, Messick T, Lieberman P. HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus. J Virol. 2016;90:5353-5367 pubmed publisher
western blot; mouse; loading ...; fig 3a	El Hokayem J, Brittain G, Nawaz Z, Bethea J. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Mol Neurobiol. 2017;54:1301-1313 pubmed publisher
western blot; mouse; 1:5000; fig 3	Lyons M, Chen L, Deng J, Finn C, Pfenning A, Sabhlok A, et al. The transcription factor calcium-response factor limits NMDA receptor-dependent transcription in the developing brain. J Neurochem. 2016;137:164-76 pubmed publisher
western blot; human; 1:1000; fig 6	Choi S, Chen Z, Tang L, Fang Y, Shin S, Panarelli N, et al. Bcl-xL promotes metastasis independent of its anti-apoptotic activity. Nat Commun. 2016;7:10384 pubmed publisher
western blot; human; 1:10,000; fig s5	Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher
western blot; human	Yu Z, Huang Y, Shieh S. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic Acids Res. 2016;44:1133-50 pubmed publisher
	Fiorucci A, Bourbousse C, Concia L, Rougée M, Deton Cabanillas A, Zabulon G, et al. Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination. Genome Biol. 2019;20:100 pubmed publisher
	Namgaladze D, Zukunft S, Schnütgen F, Kurrle N, Fleming I, Fuhrmann D, et al. Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase. Front Immunol. 2018;9:2858 pubmed publisher
	Bartlett E, Bonfiglio J, Prokhorova E, Colby T, Zobel F, Ahel I, et al. Interplay of Histone Marks with Serine ADP-Ribosylation. Cell Rep. 2018;24:3488-3502.e5 pubmed publisher
	Kress C, Montillet G, Jean C, Fuet A, Pain B. Chicken embryonic stem cells and primordial germ cells display different heterochromatic histone marks than their mammalian counterparts. Epigenetics Chromatin. 2016;9:5 pubmed publisher

product information

Catalog Number :

07-690

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3 Antibody, CT, pan

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

Histone H3

Conjugate :

Serum

Product Description :

Anti-Histone H3 Antibody, CT, pan

Cross Reactivity :

Chicken;Human;Mouse;Rat;Yeast ( S. cerevisiae )

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3;Histone H3;H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

KLH-conjugated, synthetic peptide corresponding to the C-terminus of human Histone H3.

Specificity :

Recognizes C-Terminal region of Histone H3, Mr 17 kDa

Package Size :

100 µL

Uses :

Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.