acetyl-Histone H4 (Lys12) Antibody | EMD Millipore 07-595 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H4 (Lys12) Antibody

catalog :

07-595

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, fruit fly

application :

western blot, immunocytochemistry, chromatin immunoprecipitation, ChIP-Seq

citations: 7

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; fruit fly ; loading ...; fig 4b immunocytochemistry; fruit fly ; 1:2500; loading ...; fig 4d	Scacchetti A, Schauer T, Reim A, Apostolou Z, Campos Sparr A, Krause S, et al. Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms. elife. 2020;9: pubmed publisher
chromatin immunoprecipitation; mouse; loading ...; fig 4a	Sacta M, Tharmalingam B, Coppo M, Rollins D, Deochand D, Benjamin B, et al. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. elife. 2018;7: pubmed publisher
chromatin immunoprecipitation; mouse; fig S6f	Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
	Valsecchi C, Basilicata M, Semplicio G, Georgiev P, Gutierrez N, Akhtar A. Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells. Nat Commun. 2018;9:3626 pubmed publisher
	Guertin M, Cullen A, Markowetz F, Holding A. Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq. Nucleic Acids Res. 2018;46:e75 pubmed publisher
	Zhao D, Hamilton J, Vaillancourt B, Zhang W, Eizenga G, Cui Y, et al. The unique epigenetic features of Pack-MULEs and their impact on chromosomal base composition and expression spectrum. Nucleic Acids Res. 2018;46:2380-2397 pubmed publisher
	Pan X, Fang Y, Yang X, Zheng D, Chen L, Wang L, et al. Chromatin states responsible for the regulation of differentially expressed genes under 60Co~γ ray radiation in rice. BMC Genomics. 2017;18:778 pubmed publisher

product information

Catalog Number :

07-595

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H4 (Lys12) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q6DRA9;P62805

Host Name :

Rabbit

Antigen :

acetyl-Histone H4 (Lys12)

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-acetyl-Histone H4 (Lys12) Antibody

Cross Reactivity :

Human;Yeast ( S. cerevisiae )

Background :

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

ALT Names :

H4K12Ac;Histone H4 (acetyl K12)

Immunogen :

peptide containing the sequence (LG Ac KGG) corresponding to lysine 12 acetylation of yeast Histone H4.

Specificity :

Recognizes Histone H4 acetylated on lysine 12.

Package Size :

100 μL

Uses :

Dot Blot;Western Blotting;ChIP-seq

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.