HMGB1/HMG-1 Antibody | EMD Millipore 07-584 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HMGB1/HMG-1 Antibody

catalog :

07-584

quantity :

200 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Reference
Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher

product information

Catalog Number :

07-584

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-HMGB1/HMG-1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P09429

Host Name :

Rabbit

Antigen :

HMGB1/HMG-1

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-HMGB1/HMG-1 Antibody

Cross Reactivity :

Human

Background :

HMG-1 (High-Mobility-Group protein, amphoterin) is a highly conserved protein with more than 95% amino acid identity between rodent and human HMG-1. It is a prevalent non-histone chromatin component and a non-sequence specific DNA binding protein. HMG-1 consists of two homologous HMG boxes rich in basic amino acids and an acidic tail at the carboxy-terminus. HMG-1 is involved in the regulation of chromatin structure as well as being involved, either as positive or negative factors with various aspects of DNA replication, transcription, repair, and ligation. HMG-1, identified as a membrane associated protein termed “amphoterin,” mediates neurite outgrowth, tumor outgrowth, and metastasis. It participates in plasminogen activation and is recognized as a late mediator of endotoxin lethality in mice.

ALT Names :

High mobility group protein 1;Sulfoglucuronyl carbohydrate binding protein;high mobility group box 1;high-mobility group (nonhistone chromosomal) protein 1;high-mobility group box 1

Immunogen :

HMGB1/HMG-1 protein purified from pig thymus glands.

Specificity :

Recognizes HMGB1/HMG-1, MW ~32 kDa.

Package Size :

200 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.