phospho-IRF-3 (Ser396) Antibody | EMD Millipore 07-582-I product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-IRF-3 (Ser396) Antibody

catalog :

07-582-I

quantity :

200 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, Rhesus monkey

application :

western blot

product information

Catalog Number :

07-582-I

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho-IRF-3 (Ser396) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q14653

Host Name :

Rabbit

Antigen :

phospho-IRF-3 (Ser396)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho-IRF-3 (Ser396) Antibody

Cross Reactivity :

Human

Background :

Interferon regulatory factors (IRFs) comprise a family of transcription factors that function with the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF-3 and leads to its translocation to the nucleus where it activates promoters containing IRF-3-binding sites. Phosphorylation of IRF-3 occurs at a cluster of C-terminal serine and threonine residues (between 385 and 405) leading to its association with the p300/CBP coactivator protein that promotes DNA binding and transcriptional activity.

ALT Names :

Interferon regulatory factor 3;IRF-3

Immunogen :

KLH-conjugated linear peptide corresponding to human IRF-3 phosphorylated at Ser396.

Specificity :

This antibody recognizes IRF-3 phosphorylated at Ser396.

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt