CENP-A Antibody | EMD Millipore 07-574 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CENP-A Antibody

catalog :

07-574

quantity :

200 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

07-574

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-CENP-A Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P49450

Host Name :

Rabbit

Antigen :

CENP-A

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-CENP-A Antibody

Cross Reactivity :

Human

Background :

Centromere protein A (CENP-A) is a 17 kDa centromere-specific histone variant with 62% amino acids homology to the C-terminal of histone H3. Localized in the centromere, it plays a central role in the centromere-specific chromatin formation. The depletion of histone H3 at the CENP-A binding domain suggests CENP-A to be a possible replacement for histone H3 in the packaging process of α-satellite DNA into primary chromation structure. CENP-A is essential in the formation of specialized nucleosomes at the centromere, implicating CENP-A as a centromere-specific epigenetic marker.

Immunogen :

peptide (RRRSRKPEAPRRRS) corresponding to amino acids 4-17 of human CENP-A

Specificity :

CENP-A

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2 to 8ºC from date of receipt.