PPARγ Antibody | EMD Millipore 07-466 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PPARγ Antibody

catalog :

07-466

quantity :

200 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:1000; fig 11	Wang Y, Zhu G, Wang J, Chen J. Irradiation alters the differentiation potential of bone marrow mesenchymal stem cells. Mol Med Rep. 2016;13:213-23 pubmed publisher

product information

Catalog Number :

07-466

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-PPARγ Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q53EW1

Host Name :

Rabbit

Antigen :

PPARγ

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-PPARγ Antibody

Cross Reactivity :

Human;Mouse;Vertebrates;Pig;Rabbit;Rhesus Macaque;Mink;Rat

Background :

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that can be activated by a variety of compounds including fibratus, thiazolidinediones, prostaglandins and fatty acids. Three PPAR subtypes, designated PPARα, PPARβ (also designated PPARδ) and PPARγ, have been described. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARα is abundant in primary hepatocytes where it regulates the expression of proteins involved in fatty acid metabolism. PPARβ is the most widely distributed subtype and is often expressed at high levels. PPARγ is predominantly seen in adipose tissue where it plays a critical role in regulating adipocyte differentiation.

ALT Names :

Nuclear receptor subfamily 1 group C member 1;peroxisome proliferative activated receptor, alpha;peroxisome proliferator activated receptor alpha;peroxisome proliferator-activated receptor alpha

Immunogen :

KLH-conjugated, synthetic peptide (GEDKIKFKHITPLQEQ) corresponding to amino acids 256-271 of human PPARγ1 and amino acids 287-302 of human PPARγ2. The immunizing sequence is identical in mouse and rat.

Specificity :

Recognizes PPARγ1 and 2, Mr 55-60 kDa. A non-specific protein was also detected, Mr 47 kDa after longer exposure.

Package Size :

200 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.