monomethyl-Histone H3 (Lys4) Antibody | EMD Millipore 07-436 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

monomethyl-Histone H3 (Lys4) Antibody

catalog :

07-436

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, chromatin immunoprecipitation, ChIP-Seq

citations: 11

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; human; loading ...; fig 3a	Su C, Lin I, Tzeng T, Hsieh W, Hsu M. Regulation of IL-20 Expression by Estradiol through KMT2B-Mediated Epigenetic Modification. PLoS ONE. 2016;11:e0166090 pubmed publisher
ChIP-Seq; human; loading ...; fig 1g	Platt J, Salama R, Smythies J, Choudhry H, Davies J, Hughes J, et al. Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters. EMBO Rep. 2016;17:1410-1421 pubmed
	Majumder P, Lee J, Rahmberg A, Kumar G, Mi T, Scharer C, et al. A super enhancer controls expression and chromatin architecture within the MHC class II locus. J Exp Med. 2020;217: pubmed publisher
	Kumar M, Kasti K, Balakrishnan L, Milavetz B. Directed Nucleosome Sliding during the Formation of the Simian Virus 40 Particle Exposes DNA Sequences Required for Early Transcription. J Virol. 2019;93: pubmed publisher
	Hall A, Battenhouse A, Shivram H, Morris A, Cowperthwaite M, Shpak M, et al. Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells. Cancer Res. 2018;78:2463-2474 pubmed publisher
	Fueyo R, Iacobucci S, PAPPA S, Estarás C, Lois S, Vicioso Mantis M, et al. Lineage specific transcription factors and epigenetic regulators mediate TGF?-dependent enhancer activation. Nucleic Acids Res. 2018;46:3351-3365 pubmed publisher
	Henriques T, Scruggs B, Inouye M, Muse G, Williams L, Burkholder A, et al. Widespread transcriptional pausing and elongation control at enhancers. Genes Dev. 2018;32:26-41 pubmed publisher
	Young C, Hillyer C, Hokamp K, Fitzpatrick D, Konstantinov N, Welty J, et al. Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast. BMC Genomics. 2017;18:107 pubmed publisher
	Xiaojun W, Yan L, Hong X, Xianghong Z, Shifeng L, Dingjie X, et al. Acetylated ?-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica. Sci Rep. 2016;6:32257 pubmed publisher
	Beshiri M, Holmes K, Richter W, HESS S, Islam A, Yan Q, et al. Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation. Proc Natl Acad Sci U S A. 2012;109:18499-504 pubmed publisher
	Mandal M, Powers S, Maienschein Cline M, Bartom E, Hamel K, Kee B, et al. Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat Immunol. 2011;12:1212-20 pubmed publisher

product information

Catalog Number :

07-436

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-monomethyl-Histone H3 (Lys4) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

monomethyl-Histone H3 (Lys4)

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-monomethyl-Histone H3 (Lys4) Antibody

Cross Reactivity :

Human;Vertebrates

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3K4me1;Histone H3 (mono methyl K4);H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

KLH-conjugated, synthetic peptide containing the sequence ART[meK]…, in which meK corresponds to monomethyl-lysine at residue 4 of human histone H3.

Specificity :

Recognizes monomethyl-histone H3 (Lys4), Mr 17kDa.

Package Size :

200 µg

Uses :

Immunocytochemistry;Immunofluorescence;Peptide Inhibition Assay;Western Blotting;ChIP-seq;Dot Blot

Storage :

Stable for 1 year at 2 to 8°C from date of receipt.