dimethyl-Arginine Antibody, asymmetric (ASYM24) | EMD Millipore 07-414 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

dimethyl-Arginine Antibody, asymmetric (ASYM24)

catalog :

07-414

quantity :

200 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig e1	Zhao D, Gish G, Braunschweig U, Li Y, Ni Z, Schmitges F, et al. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. 2016;529:48-53 pubmed publisher
	Lu Y, Ma W, Li Z, Lu J, Wang X. The interplay between p16 serine phosphorylation and arginine methylation determines its function in modulating cellular apoptosis and senescence. Sci Rep. 2017;7:41390 pubmed publisher
	Eberhardt A, Hansen J, Koster J, Lotta L, Wang S, Livingstone E, et al. Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma. Oncotarget. 2016;7:63629-63639 pubmed publisher

product information

Catalog Number :

07-414

Subcategory :

Cell Signaling

Product Name :

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM24)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Host Name :

Rabbit

Antigen :

dimethyl-Arginine

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM24)

Cross Reactivity :

Human;Mouse

Background :

Arginine methylation is a post-translational modification that results in the formation of asymmetrical and symmetrical dimethylated arginines (a- and sDMA).

Immunogen :

KLH-conjugated, synthetic peptide containing asymmetric dimethyl-arginine-glycine repeats (KGR*GR*GR*GR*GPPPPPR*GR*GR*GR*G in which R* denotes asymmetric dimethylation of arginine).

Specificity :

Recognizes proteins that contain arginines that are asymmetrically dimethylated including p300, p110, p75 and Sam68. Specificity for asymmetrically dimethylated arginine was determined by ELISA with an unmethylated ‘backbone’ peptide or an identical peptide containing symmetrically dimethylated arginines.

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.