This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Histone H2B Antibody
catalog :
07-371
quantity :
200 μg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, Xenopus laevis, thale cress
application :
western blot, chromatin immunoprecipitation
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; thale cress; loading ...; fig s9a
Jiang D, Berger F. DNA replication-coupled histone modification maintains Polycomb gene silencing in plants. Science. 2017;357:1146-1149 pubmed publisher
  • western blot; mouse; loading ...; fig 1d
Honda M, Hidaka K, Fukada S, Sugawa R, Shirai M, Ikawa M, et al. Vestigial-like 2 contributes to normal muscle fiber type distribution in mice. Sci Rep. 2017;7:7168 pubmed publisher
  • western blot; human; loading ...; fig 4a
  • western blot; mouse; loading ...; fig 4a
Luo D, de Morrée A, Boutet S, Quach N, Natu V, Rustagi A, et al. Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c. Proc Natl Acad Sci U S A. 2017;114:E3071-E3080 pubmed publisher
  • chromatin immunoprecipitation; human; fig 6
Kang M, Park K, Yang J, Lee C, Oh S, Yun J, et al. miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells. PLoS ONE. 2016;11:e0160961 pubmed publisher
  • western blot; Xenopus laevis; 1:2000; fig 8
Simon A, Sannino V, Costanzo V, Pellegrini L. Structure of human Cdc45 and implications for CMG helicase function. Nat Commun. 2016;7:11638 pubmed publisher
  • western blot; human; 1:2000; fig 3
Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed publisher
Sampadi B, Pines A, Munk S, Misovic B, de Groot A, van de Water B, et al. Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action. Arch Toxicol. 2020;94:1655-1671 pubmed publisher
Chernikova S, Nguyen R, Truong J, Mello S, Stafford J, Hay M, et al. Dynamin impacts homology-directed repair and breast cancer response to chemotherapy. J Clin Invest. 2018;128:5307-5321 pubmed publisher
Schwarzer W, Abdennur N, Goloborodko A, Pekowska A, Fudenberg G, Loe Mie Y, et al. Two independent modes of chromatin organization revealed by cohesin removal. Nature. 2017;551:51-56 pubmed publisher
Spolverini A, Fuchs G, Bublik D, Oren M. let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery. Oncogene. 2017;36:5819-5828 pubmed publisher
Lee B, Lee J, Shen W, Rhee C, Chung H, Kim J. Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination. Nucleic Acids Res. 2017;45:7151-7166 pubmed publisher
Bulusu V, Prior N, Snaebjornsson M, Kuehne A, Sonnen K, Kress J, et al. Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017;40:331-341.e4 pubmed publisher
Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, et al. Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. J Biol Chem. 2017;292:4727-4742 pubmed publisher
Hait N, Wise L, Allegood J, O Brien M, Avni D, Reeves T, et al. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci. 2014;17:971-80 pubmed publisher
product information
Catalog Number :
07-371
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-Histone H2B Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
Q8N257
Host Name :
Rabbit
Antigen :
Histone H2B
Conjugate :
Purified
Isotype :
IgG
Product Description :
Anti-Histone H2B Antibody
Cross Reactivity :
Chicken;Xenopus;Human;Yeast ( S. cerevisiae )
Background :
Histone H2B is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the 'beads on a string' structure.
ALT Names :
H2B;Histone H2B;H2B histone family, member Q;histone 2, H2be;histone cluster 2, H2be
Immunogen :
KLH-conjugated, synthetic peptide corresponding to amino acids 118-126 (CG-AVTKYTSSK) of human Histone H2B, with an N-terminal CG added for conjugation purposes.
Specificity :
Recognizes and is specific for Histone H2B, MW ~15 kDa. An additional band at ~23 kDa is detected in some samples, which likely corresponds to ubiquityl-Histone H2B.
Package Size :
200 μg
Uses :
Western Blotting;Chromatin Immunoprecipitation (ChIP)
Storage :
Stable for 1 year at -20ºC from date of receipt.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.