acetyl-Histone H3 (Lys27) Antibody | EMD Millipore 07-360 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H3 (Lys27) Antibody

catalog :

07-360

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation, ChIP-Seq

citations: 18

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; loading ...; fig 3k	Carpenter M, Hu Q, Bond A, Lombroso S, Czarnecki K, Lim C, et al. Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes. Nat Commun. 2020;11:504 pubmed publisher
ChIP-Seq; mouse; loading ...; fig s4a	Peterson J, Wang D, Shettigar V, Roof S, Canan B, Bakkar N, et al. NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nat Commun. 2018;9:3431 pubmed publisher
ChIP-Seq; mouse; loading ...; fig 5a	Wu H, Gordon J, Whitfield T, Tai P, Van Wijnen A, Stein J, et al. Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis. Biochim Biophys Acta Gene Regul Mech. 2017;1860:438-449 pubmed publisher
western blot; human; loading ...; fig 2a	Shirakawa K, Wang L, Man N, Maksimoska J, Sorum A, Lim H, et al. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. elife. 2016;5: pubmed publisher
western blot; human; fig 4s1	Conery A, Centore R, Neiss A, Keller P, Joshi S, Spillane K, et al. Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma. elife. 2016;5: pubmed publisher
	Nandymazumdar M, Yin S, Paranjapye A, Kerschner J, Swahn H, Ge A, et al. Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells. Nucleic Acids Res. 2020;48:3513-3524 pubmed publisher
	Majumder P, Lee J, Rahmberg A, Kumar G, Mi T, Scharer C, et al. A super enhancer controls expression and chromatin architecture within the MHC class II locus. J Exp Med. 2020;217: pubmed publisher
	Benabdallah N, Williamson I, Illingworth R, Kane L, Boyle S, Sengupta D, et al. Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation. Mol Cell. 2019;76:473-484.e7 pubmed publisher
	Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, et al. The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Cell Rep. 2019;27:3533-3546.e7 pubmed publisher
	de Almeida B, Noronha R, da Costa M, Nagamachi C, Pieczarka J. Meiosis in the scorpion Tityus silvestris: new insights into achiasmatic chromosomes. Biol Open. 2019;8: pubmed publisher
	Chen J, Lazarenko O, Zhao H, Alund A, Shankar K. Maternal obesity impairs skeletal development in adult offspring. J Endocrinol. 2018;239:33–47 pubmed publisher
	Numata A, Kwok H, Kawasaki A, Li J, Zhou Q, Kerry J, et al. The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia. Nat Commun. 2018;9:1622 pubmed publisher
	Gawrzak S, Rinaldi L, Gregorio S, Arenas E, Salvador F, Urosevic J, et al. MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer. Nat Cell Biol. 2018;20:211-221 pubmed publisher
	Griggs C, Malm S, Jaime Frias R, Smith C. Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicol Appl Pharmacol. 2018;339:110-120 pubmed publisher
	Read K, Powell M, Baker C, Sreekumar B, Ringel Scaia V, Bachus H, et al. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells. J Immunol. 2017;199:2377-2387 pubmed publisher
	Pappas K, Xu J, Zairis S, Resnick Silverman L, Abate F, Steinbach N, et al. p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes. Mol Cancer Res. 2017;15:1051-1062 pubmed publisher
	Ferreira R, Popova E, James J, Briones M, Zhang S, Barnstable C. Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina. J Biol Chem. 2017;292:2422-2440 pubmed publisher
	Lubecka K, Kurzava L, Flower K, Buvala H, Zhang H, Teegarden D, et al. Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity. Carcinogenesis. 2016;37:656-68 pubmed publisher

product information

Catalog Number :

07-360

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H3 (Lys27) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

acetyl-Histone H3 (Lys27)

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-acetyl-Histone H3 (Lys27) Antibody

Cross Reactivity :

Human;Vertebrates;Yeast ( S. cerevisiae )

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3K27Ac;Histone H3 (acetyl K27)

Immunogen :

synthetic peptide corresponding to the sequence ARACKSA, in which ACK corresponds to acetyl lysine 27 of yeast histone H3

Specificity :

Recognizes Histone H3 acetylated on lysine 27.

Package Size :

100 μL

Uses :

Western Blotting;ChIP-seq;Chromatin Immunoprecipitation (ChIP);Dot Blot

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.