acetyl-Histone H3 (Lys23) Antibody | EMD Millipore 07-355 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H3 (Lys23) Antibody

catalog :

07-355

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, chromatin immunoprecipitation

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; loading ...; fig 2c	Wang Z, Millard C, Lin C, Gurnett J, Wu M, Lee K, et al. Diverse nucleosome site-selectivity among histone deacetylase complexes. elife. 2020;9: pubmed publisher
immunocytochemistry; mouse; fig 8d western blot; mouse; loading ...; fig 8a	You L, Li L, Zou J, Yan K, Belle J, Nijnik A, et al. BRPF1 is essential for development of fetal hematopoietic stem cells. J Clin Invest. 2016;126:3247-62 pubmed publisher
	Xi Y, Shi J, Li W, Tanaka K, Allton K, Richardson D, et al. Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes. BMC Genomics. 2018;19:150 pubmed publisher
	Lv D, Jia F, Hou Y, Sang Y, Alvarez A, Zhang W, et al. Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding. Cancer Res. 2017;77:6190-6201 pubmed publisher
	Wang L, Zhang F, Rode S, Chin K, Ko E, Kim J, et al. Ethylene induces combinatorial effects of histone H3 acetylation in gene expression in Arabidopsis. BMC Genomics. 2017;18:538 pubmed publisher
	Hait N, Wise L, Allegood J, O Brien M, Avni D, Reeves T, et al. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci. 2014;17:971-80 pubmed publisher

product information

Catalog Number :

07-355

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H3 (Lys23) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

acetyl-Histone H3 (Lys23)

Conjugate :

Serum

Product Description :

Anti-acetyl-Histone H3 (Lys23) Antibody

Cross Reactivity :

Human;Vertebrates;Yeast ( S. cerevisiae )

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

H3K23Ac;Histone H3 (acetyl K23)

Immunogen :

Ovalbumin-conjugated, synthetic peptide (KQLAS Ac KAARK-C) corresponding to amino acids 18-27 of yeast histone H3 acetylated on lysine 23 with a C-terminal cysteine added for conjugation purposes

Specificity :

Histone H3 acetylated on lysine 23. Does not recognize unacetylated recombinant histone H3

Package Size :

100 µL

Uses :

Western Blotting;Dot Blot;Chromatin Immunoprecipitation (ChIP)

Storage :

2 years at -20°C