acetyl-Histone H3 (Lys18) Antibody | EMD Millipore 07-354 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H3 (Lys18) Antibody

catalog :

07-354

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, brewer's yeast

application :

western blot, chromatin immunoprecipitation, ChIP-Seq

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; loading ...; fig 2c	Wang Z, Millard C, Lin C, Gurnett J, Wu M, Lee K, et al. Diverse nucleosome site-selectivity among histone deacetylase complexes. elife. 2020;9: pubmed publisher
ChIP-Seq; brewer's yeast; loading ...; fig 5c western blot; brewer's yeast; loading ...; fig 5s1a	Donczew R, Warfield L, Pacheco D, Erijman A, Hahn S. Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA. elife. 2020;9: pubmed publisher
ChIP-Seq; human; loading ...; fig 3b	Nava M, Dutta P, Zemke N, Farias Eisner R, Vadgama J, Wu Y. Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets. BMC Med Genomics. 2019;12:32 pubmed publisher
western blot; mouse; loading ...; fig 8b	You L, Li L, Zou J, Yan K, Belle J, Nijnik A, et al. BRPF1 is essential for development of fetal hematopoietic stem cells. J Clin Invest. 2016;126:3247-62 pubmed publisher
chromatin immunoprecipitation; human; fig 3	Zhao L, Loewenstein P, Green M. The adenoviral E1A N-terminal domain represses MYC transcription in human cancer cells by targeting both p300 and TRRAP and inhibiting MYC promoter acetylation of H3K18 and H4K16. Genes Cancer. 2016;7:98-109 pubmed publisher
	Hait N, Wise L, Allegood J, O Brien M, Avni D, Reeves T, et al. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory. Nat Neurosci. 2014;17:971-80 pubmed publisher

product information

Catalog Number :

07-354

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H3 (Lys18) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

acetyl-Histone H3 (Lys18)

Conjugate :

Serum

Product Description :

Anti-acetyl-Histone H3 (Lys18) Antibody

Cross Reactivity :

Human;Vertebrates;Yeast ( S. cerevisiae )

Background :

Histone H3 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

ALT Names :

H3K18Ac;Histone H3 (acetyl K18)

Immunogen :

KLH-conjugated, synthetic peptide (GKAPRAcKQLASK-C) corresponding to amino acids 13-23 of yeast Histone H3 acetylated on lysine 18with a C-terminal cysteine added for conjugation purposes

Specificity :

Recognizes Histone H3 acetylated on lysine 18.

Package Size :

100 μL

Uses :

Western Blotting;Dot Blot;Chromatin Immunoprecipitation (ChIP);ChIP-seq

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.