acetyl-Histone H4 (Lys5) Antibody | EMD Millipore 07-327 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H4 (Lys5) Antibody

catalog :

07-327

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, chromatin immunoprecipitation

citations: 5

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; mouse; loading ...; fig 4a	Sacta M, Tharmalingam B, Coppo M, Rollins D, Deochand D, Benjamin B, et al. Gene-specific mechanisms direct glucocorticoid-receptor-driven repression of inflammatory response genes in macrophages. elife. 2018;7: pubmed publisher
	Kopinski P, Janssen K, Schaefer P, Trefely S, Perry C, Potluri P, et al. Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy. Proc Natl Acad Sci U S A. 2019;116:16028-16035 pubmed publisher
	Valsecchi C, Basilicata M, Semplicio G, Georgiev P, Gutierrez N, Akhtar A. Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells. Nat Commun. 2018;9:3626 pubmed publisher
	Saavedra F, Rivera C, Rivas E, Merino P, Garrido D, Hernandez S, et al. PP32 and SET/TAF-I? proteins regulate the acetylation of newly synthesized histone H4. Nucleic Acids Res. 2017;45:11700-11710 pubmed publisher
	Wu D, Zhao L, Feng Z, Yu C, Ding J, Wang L, et al. O-Linked N-acetylglucosamine transferase 1 regulates global histone H4 acetylation via stabilization of the nonspecific lethal protein NSL3. J Biol Chem. 2017;292:10014-10025 pubmed publisher

product information

Catalog Number :

07-327

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H4 (Lys5) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P62805

Host Name :

Rabbit

Antigen :

acetyl-Histone H4 (Lys5)

Conjugate :

Serum

Product Description :

Anti-acetyl-Histone H4 (Lys5) Antibody

Cross Reactivity :

Human

Background :

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

ALT Names :

Histone H4

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of Histone H4 acetylated at Lys5.

Specificity :

This antibody recognizes the N-terminus of Histone H4 acetylated at Lys5.

Package Size :

100 µL

Uses :

Western Blotting;Dot Blot;Immunocytochemistry;ChIP-seq;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.