This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
FSP1/S100A4 Antibody
catalog :
07-2274
quantity :
100 μg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 5e
Engelbrecht E, Lévesque M, He L, Vanlandewijck M, Nitzsche A, Niazi H, et al. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. elife. 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250–1:500; fig s121
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed publisher
  • immunohistochemistry; human; 1:300; loading ...; fig 2c
  • western blot; human; loading ...; fig 2c
Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, et al. Pericyte-fibroblast transition promotes tumor growth and metastasis. Proc Natl Acad Sci U S A. 2016;113:E5618-27 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; tbl 1
  • western blot; mouse; 1:1000; tbl 2
Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3
  • flow cytometry; mouse; fig 3
Yin S, Jian F, Chen Y, Chien S, Hsieh M, Hsiao P, et al. Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis. Nat Commun. 2016;7:11311 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Huang M, Liu T, Ma P, Mitteer R, Zhang Z, Kim H, et al. c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest. 2016;126:1801-14 pubmed publisher
  • western blot; human; fig 5f
Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, et al. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016;8:6-24 pubmed publisher
Lee E, Yeo S, Lee K, Lee J, Kim K, Kim S. New screening system using Twist1 promoter activity identifies dihydrorotenone as a potent drug targeting cancer-associated fibroblasts. Sci Rep. 2020;10:7058 pubmed publisher
Sharma A, Kilari S, Cai C, Simeon M, Misra S. Increased fibrotic signaling in a murine model for intra-arterial contrast-induced acute kidney injury. Am J Physiol Renal Physiol. 2020;318:F1210-F1219 pubmed publisher
Liu T, Ma W, Xu H, Huang M, Zhang D, He Z, et al. PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma. Nat Commun. 2018;9:3439 pubmed publisher
Schulz D, Zanotelli V, Fischer J, Schapiro D, Engler S, Lun X, et al. Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry. Cell Syst. 2018;6:25-36.e5 pubmed publisher
product information
Catalog Number :
07-2274
Subcategory :
Cell Signaling
Product Name :
Anti-FSP1/S100A4 Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
P07091
Host Name :
Rabbit
Antigen :
FSP1/S100A4
Conjugate :
Purified
Isotype :
IgG
Product Description :
Anti-FSP1/S100A4 Antibody
Cross Reactivity :
Mouse;Human
Background :
Fibroblast-specific protein-1 (FSP1)/S100A4 is a cytoplasmic calcium-binding protein belonging to the S100 superfamily of which at least 21 members have been identified so far. Researchers believe that FSP1/S1004A is highly expressed in fibroblasts (Iwano et al., 2001; Strutz et al., 1995), in epithelial and endothelial cells undergoing epithelial-mesenchymal transition (EMT) (Iwano et al., 2002; Zeisberg and Neilson, 2009), and epithelial cancer cells that complete a transition to a metastatic phenotype (Xue et al., 2003).
ALT Names :
S100 calcium binding protein A4;S100 calcium-binding protein A4;fibroblast-specific protein-1;leukemia multidrug resistance associated protein;S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog);malignant transformation suppression 1;S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog);Metastasin;Protein Mts1;Placental calcium-binding protein;Calvasculin
Immunogen :
Histidine-tagged recombinant protein corresponding to mouse FSP1/S100-A4.
Package Size :
100 μg
Uses :
Western Blotting;Immunohistochemistry (Paraffin)
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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