phospho-RalA Antibody (Ser194) | EMD Millipore 07-2119 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-RalA Antibody (Ser194)

catalog :

07-2119

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, rat, cow, zebrafish

application :

western blot

product information

Catalog Number :

07-2119

Subcategory :

Cell Signaling

Product Name :

Anti-phospho-RalA Antibody (Ser194)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P11233

Host Name :

Rabbit

Antigen :

phospho-RalA (Ser194)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho-RalA Antibody (Ser194)

Cross Reactivity :

Human;Bovine;Rat;Xenopus;Zebrafish

Background :

RalA and RalB are Ras-family small monomeric GTPases that can be activated through a Ras-dependent mechanism. The two are highly homologous (89%). Ral proteins are proximal effectors of oncogenic Ras and their activity is needed to support tumorigenesis in certain cancers. Mutants of Ras that are defective in activating all known Ras effectors except Ral GEF are still able to induce invasive phenotypes in transfected cells, suggesting a role for Ral in these processes. RalA is required for anchorage-independent proliferation and tumorigeneisis by driving exocyst assembly and polarized exocytosis in epithelial cells.

ALT Names :

Ras-related protein Ral-A

Immunogen :

KLH-conjugated linear peptide corresponding to human RalA phosphorylated at Ser194.

Specificity :

This antibody recognizes RalA phosphorylated at Ser194.

Package Size :

100 μg

Uses :

Western Blotting;Peptide Inhibition Assay

Storage :

Stable for 1 year at 2-8°C from date of receipt