dimethyl (Lys4) dimethyl (Lys9) Histone H3 Antibody | EMD Millipore 07-1843 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

dimethyl (Lys4) dimethyl (Lys9) Histone H3 Antibody

catalog :

07-1843

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation, chromatin immunoprecipitation

product information

Catalog Number :

07-1843

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-dimethyl (Lys4) dimethyl (Lys9) Histone H3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P84243

Host Name :

Rabbit

Antigen :

dimethyl (Lys4) dimethyl (Lys9) Histone H3

Conjugate :

Affinity Purified

Product Description :

Anti-dimethyl (Lys4) dimethyl (Lys9) Histone H3 Antibody

Cross Reactivity :

Human;Vertebrates

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Acetylation of histone H3 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Acetylation of lysine14 is commonly seen in genes that are being actively transcribed into RNA.

ALT Names :

H3K4me2K9me2;Histone H3 (di methyl K4, di methyl K9);H3 histone, family 3A

Immunogen :

Synthetic peptide corresponding to residues surrounding and including dimethlyated Lys 4 and dimethlyated Lys9 of Histone H3.

Specificity :

This antibody only detects Histone H3 when dimethylated on both Lysine 4 and Lys9.

Package Size :

100 µL

Uses :

Western Blotting;Multiplexing;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8ºC from date of receipt.