acetyl-Tip60 Antibody (Lys523) | EMD Millipore 07-1841 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Tip60 Antibody (Lys523)

catalog :

07-1841

quantity :

200 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, cow

application :

western blot

product information

Catalog Number :

07-1841

Subcategory :

Cell Signaling

Product Name :

Anti-acetyl-Tip60 Antibody (Lys523)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q92993-3

Host Name :

Rabbit

Antigen :

acetyl-Tip60 (Lys523)

Conjugate :

Affinity Purified

Product Description :

Anti-acetyl-Tip60 Antibody (Lys523)

Cross Reactivity :

Human;Mouse;Bovine;Porcine

Background :

Histone acetyltransferase HTATIP (Tip60) is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Direct binding of HTATIP to the TAT protein of the human immunodeficiency virus (HIV) might be an important feature for efficient TAT transactivation of HIV gene expression.

ALT Names :

Histone acetyltransferase KAT5;60 kDa Tat-interactive protein;Tip60;Histone acetyltransferase HTATIP;HIV-1 Tat interactive protein;Lysine acetyltransferase 5;cPLA(2)-interacting protein;KAT5;Histone acetyltransferase KAT5

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human Tip60 acetylated at Lys523.

Specificity :

This antibody recognizes the C-terminus of Tip60 acetylated at Lys523. This antibody is expect to react with all four known isoforms.

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt