EEA1 Antibody | EMD Millipore 07-1820 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

EEA1 Antibody

catalog :

07-1820

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, bovine

application :

western blot, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 2	Polanco J, Scicluna B, Hill A, Götz J. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner. J Biol Chem. 2016;291:12445-66 pubmed publisher
	Shi L, Muthusamy N, Smith D, Bergson C. Dynein binds and stimulates axonal motility of the endosome adaptor and NEEP21 family member, calcyon. Int J Biochem Cell Biol. 2017;90:93-102 pubmed publisher

product information

Catalog Number :

07-1820

Subcategory :

Cell Signaling

Product Name :

Anti-EEA1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q15075

Host Name :

Rabbit

Antigen :

EEA1

Conjugate :

Affinity Purified

Product Description :

Anti-EEA1 Antibody

Cross Reactivity :

Human;Mouse

Background :

Early endosome antigen 1 (EEA1) is a 170 kDa coiled-coil protein belonging to a group of early endosomal Rab5 effector proteins. EEA1 has a putative role in the tethering/docking of endocytic vesicles prior to their fusion with early endosomes. This protein is characterized as containing a zinc finger-like domain and coiled-coil regions. The zinc finger-like domain, also known as the FYVE finger, is a motif rich in cystine, is a necessary component of EEA1’s ability for endosomal targeting, and is specifically known for its dual interaction with Rab5 GTPase and phosphotidylinositol 3-phosphate (Ptdlns-3-P).

ALT Names :

early endosome antigen 1;early endosome-associated protein;early endosome antigen 1, 162kD;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2

Immunogen :

GST-tagged recombinant protein corresponding to the C-terminus of human EEA1.

Specificity :

This antibody recognizes EEA1.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt