G3BP1 Antibody | EMD Millipore 07-1801 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

G3BP1 Antibody

catalog :

07-1801

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2 immunoprecipitation; mouse; fig 2 western blot; mouse; fig 2	Gal J, Kuang L, Barnett K, Zhu B, Shissler S, Korotkov K, et al. ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics. Acta Neuropathol. 2016;132:563-76 pubmed publisher

product information

Catalog Number :

07-1801

Subcategory :

Cell Signaling

Product Name :

Anti-G3BP1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q13884

Host Name :

Rabbit

Antigen :

G3BP1

Conjugate :

Serum

Product Description :

Anti-G3BP1 Antibody

Cross Reactivity :

Mouse;Human;Rat

Background :

G3BP1 (Ras-GTPase activating protein SH3-domain binding protein 1) directly associates with SH3 domains of GTPase activating proteins (GAPs). It was first discovered by its binding to RasGAP. G3BPs have been shown to be involved in a number of mitogenic signaling pathways. G3BP1 is also known to be over expressed in many human cancers (Kim, 2007) and its expression appears to be inversely correlated with PTEN expression (Kim, 2007). Interestingly, G3BP1, along with G3BP2, has been shown to bind to the C-terminus of p53, playing a crucial role in its activity (Kim, 2007). Furthermore, the G3BPs have two traditional RNA binding motifs.

ALT Names :

ATP-dependent DNA helicase VIII ;GAP SH3 domain-binding protein 1;GAP binding protein;GTPase activating protein (SH3 domain) binding protein 1;Ras-GTPase-activating protein SH3-domain-binding protein;RasGAP-associated endoribonuclease G3BP

Immunogen :

Synthetic peptide corresponding to C-terminal region of human G3BP1.

Specificity :

This antibody detects G3BP1 at its C-terminal region.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at -20ºC from date of receipt.