eIF4G Antibody | EMD Millipore 07-1800 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

eIF4G Antibody

catalog :

07-1800

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

07-1800

Subcategory :

Cell Signaling

Product Name :

Anti-eIF4G Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q04637

Host Name :

Rabbit

Antigen :

eIF4G

Conjugate :

Serum

Product Description :

Anti-eIF4G Antibody

Cross Reactivity :

Human;Mouse

Background :

eIF4F is a translation initiation factor containing three subunits: eIF4A, eIF4E, and eIF4G. This complex is a key component in promoting ribosomal binding to the mRNA. eIF4G interacts with both eIF4A and eIF4E though its carboxy and amino terminal domains, respectively. eIF4E binds to the cap structure of the mRNA, while the ATP-dependent RNA helicase eIF4A unwinds the secondary structure of the 5’ UTR. eIF4G plays a critical role in coordinating the assembly of the eukaryotic initiation factors. It acts as a bridge to bind the cap-bound eIF4E, eIF4AI&II, the eIF3 complex, PABP1, and the kinase Mnk1 (Lejeune, F., et al., 2004) in a large eukaryotic initiation factor complex

ALT Names :

eIF-4-gamma 1;eIF-4G 1 ;eukaryotic translation initiation factor 4 gamma, 1

Immunogen :

Synthetic peptide corresponding to N-terminal region of human eIF4G.

Specificity :

This antibody detects eIF4G at its N-terminal region.

Package Size :

100 µL

Uses :

Western Blotting;Immunofluorescence

Storage :

Stable for 1 year at -20ºC from date of receipt.