JMJD3 Antibody (CT) | EMD Millipore 07-1534 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

JMJD3 Antibody (CT)

catalog :

07-1534

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 10c	Achuthan A, Cook A, Lee M, Saleh R, Khiew H, Chang M, et al. Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation. J Clin Invest. 2016;126:3453-66 pubmed publisher
	Dhawan S, Dirice E, Kulkarni R, Bhushan A. Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication. Diabetes. 2016;65:1208-18 pubmed publisher

product information

Catalog Number :

07-1534

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-JMJD3 Antibody (CT)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O15054

Host Name :

Rabbit

Antigen :

JMJD3 (CT)

Conjugate :

Purified

Product Description :

Anti-JMJD3 Antibody (CT)

Cross Reactivity :

Human;Mouse

Background :

JMJD3 (Jumonji domain-containing protein 3) is part of the family of novel JmjC domain-containing histone demethylation (JHDM) enzymes. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. JMJD3 specifically demethylates Lys27 on histone H3, demethylating both the trimethylated and dimethylated form. JMJD3 plays a role in the regulation of posterior development by regulating HOX gene expression. It is also involved in the inflammatory response by regulating gene expression and macrophage differentiation

ALT Names :

JMJD;JmjC domain-containing protein 3 ;Jumonji domain-containing protein 3;Lysine demethylase 6B;jumonji domain containing 3 ;jumonji domain containing 3, histone lysine demethylase

Immunogen :

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of murine JMJD3.

Specificity :

Recognizes the C-terminal region of murine JMJD3. Additional non-specific, lower molecular weight bands are detected in some lysates.

Package Size :

100 μg

Uses :

Immunocytochemistry;ELISA;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial to pellet the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.