cAMP Antibody | EMD Millipore 07-1497 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

cAMP Antibody

catalog :

07-1497

quantity :

50 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 1

Reference
Havekes R, Park A, Tolentino R, Bruinenberg V, Tudor J, Lee Y, et al. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. J Neurosci. 2016;36:8936-46 pubmed publisher

product information

Catalog Number :

07-1497

Subcategory :

Cell Signaling

Product Name :

Anti-cAMP Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Host Name :

Rabbit

Antigen :

cAMP

Conjugate :

Serum

Product Description :

Anti-cAMP Antibody

Cross Reactivity :

Rat

Background :

Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates the effects of glucagon and adrenaline along with the movement of calcium ions through ion channels. Since it is affected directly by GPCR activation, cAMP is studied as a means to monitor GPCR in the discovery of therapeutic drugs.

Immunogen :

2'O-succinyl cyclic AMP conjugated to BSA

Specificity :

Specific for cAMP with no cross reaction to other nucleotides at concentrations to 1 mM. Reactive with cAMP fixed in tissues or acetylated cAMP. Not reactive with free, non-acetylated, cAMP in RIA or EIA assays.

Package Size :

50 μL

Uses :

Immunohistochemistry (Paraffin)

Storage :

Maintain at -20°C in undiluted aliquots from date of shipment. Avoid repeated freeze/thaw cycles.