CaM Kinase II Antibody | EMD Millipore 07-1496 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CaM Kinase II Antibody

catalog :

07-1496

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken, bovine

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 1c	Prasad A, Ketsawatsomkron P, Nuno D, Koval O, Dibbern M, Venema A, et al. Role of CaMKII in Ang-II-dependent small artery remodeling. Vascul Pharmacol. 2016;87:172-179 pubmed publisher
western blot; mouse; fig 7	Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher

product information

Catalog Number :

07-1496

Subcategory :

Cell Signaling

Product Name :

Anti-CaM Kinase II Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9UQM7

Host Name :

Rabbit

Antigen :

CaM Kinase II

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-CaM Kinase II Antibody

Cross Reactivity :

Human;Rat;Mouse;Bovine;Hamster;Guinea Pig;Chicken;Rabbit

Background :

The Ca2+/Calmodulin-Dependent Kinase family includes CaM Kinases I through IV, Phosphorylase Kinase, and MLCK. The CaM Kinases are inactive in the absence of stimuli; binding to Ca2+/Calmodulin induces conformational changes and activation. CaM Kinases have broad substrate specificity, with many cellular functions.

Immunogen :

Synthetic peptide corresponding to the N-terminus of Rat CaMK II

Specificity :

Recognizes proteins of 50-72 kDa, corresponding to apparent molecular mass of CaMKII isoforms on SDS-PAGE immunoblots. Recombinant rat calmodulin-dependent protein kinase II α subunits expressed in sf9 insect cells are also detected. As the sequences of the rat α, δ, and γ isoforms are conserved over this amino terminus region, this antibody is expected to recognize the δ, γ, and α isoforms. Antibody is not expected to cross-react with the β isoform. Proteins of unknown identity may be detected on immunoblot analysis with some lysates (40, 45 and 90 kDa).

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C in undiluted aliquots from date of receipt. For optimal storage, aliquot and store at -20°C or -70°C. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.