Rac1 Antibody | EMD Millipore 07-1464 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rac1 Antibody

catalog :

07-1464

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

07-1464

Subcategory :

Cell Signaling

Product Name :

Anti-Rac1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P63000

Host Name :

Rabbit

Antigen :

Rac1

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Rac1 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

Rac is a member of the Rho family of small GTP-binding proteins, and plays roles in cytoskeletal actin organization as well as transformation. Rac is activated downstream of cdc42, or independently by Ras signaling, and in turn Rac stimulates Rho. Activation of Rac results in the formation of lamellipodia, whereas cdc42 stimulates filopodia formation, and Rho stimulates formation of actin stress fibers. Effectors of the Rac pathway include NADPH Oxidase and the SAPK1/JNK family of kinases. The latter pathway is activated by the PAK kinases, which are direct targets of Rac.

ALT Names :

Ras-related C3 Botulinum Toxin Substrate 1;p21-Rac1;Ras-like Protein TC25

Immunogen :

Synthetic peptide corresponding to amino acids 130-141 of human Rac1 (KEKKLTPITYPQ-C).

Specificity :

Recognizes Rac1, does not cross react with Cdc42. Rac1 is a member of the Rho family of small GTPases. Small GTPases act as molecular switches in regulating a variety of biological response pathways by cycling from the GDP-bound (inactive) and GTP-bound (active) states. Rac regulates actin polymerization to form lamellipodia.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable at 2-8°C in undiluted aliquots for up to 6 months from date of receipt.