PDGF-BB Antibody | EMD Millipore 07-1437 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PDGF-BB Antibody

catalog :

07-1437

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, neutralization

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 6a	Jiang Y, Lin X, Tang Z, Lee C, Tian G, Du Y, et al. Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK. Proc Natl Acad Sci U S A. 2017;114:10737-10742 pubmed publisher

product information

Catalog Number :

07-1437

Subcategory :

Cell Signaling

Product Name :

Anti-PDGF-BB Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P01127

Host Name :

Rabbit

Antigen :

PDGF-BB

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-PDGF-BB Antibody

Cross Reactivity :

Human

Background :

Platelet-Derived Growth Factor (PDGF) is a dimer of A (17 kDa) and B (14 kDa) chains (AA, AB, or BB). Its receptors are transmembrane receptor tyrosine kinases, PDGF Receptors type A and B. The type A PDGF receptor binds all three PDGFs with high affinity, whereas the type B PDGF receptor is selective for PDGF-BB. PDGF signals as a growth and survival factor, as it is a potent activator of the PI3 Kinase pathway. PDGF signaling appears to play an essential role in the development of tumors of glial origin.

ALT Names :

Platelet-derived growth factor B chain precursor;Platelet-derived growth factor beta polypeptide;Platelet-derived growth factor, beta polypeptide (oncogene SIS) oncogene SIS;Platelet-derived growth factor;Platelet-derived growth factor beta;Platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog);Platelet-derived growth factor, B chain;V-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)

Immunogen :

Highly purified ( 98%) recombinant human PDGF-BB

Specificity :

Reacts with human PDGF-BB.

Package Size :

100 μL

Uses :

Western Blotting;ELISA;Neutralizing

Storage :

Maintain lyophilized material desiccated below 0°C. After reconstitution maintain at -20°C in convenient undiluted aliquots for up to 6 months from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.