GLUT-4 Antibody, C-terminus 07-1404 | EMD Millipore 07-1404 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GLUT-4 Antibody, C-terminus 07-1404

catalog :

07-1404

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, ELISA, immunohistochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2h	Riis S, Christensen B, Nellemann B, Møller A, Husted A, Pedersen S, et al. Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males. J Appl Physiol (1985). 2019;126:569-577 pubmed publisher
western blot; mouse; loading ...; fig 5d	Martins F, Bargut T, Aguila M, Mandarim de Lacerda C. Thermogenesis, fatty acid synthesis with oxidation, and inflammation in the brown adipose tissue of ob/ob (-/-) mice. Ann Anat. 2017;210:44-51 pubmed publisher
western blot; rat; loading ...; fig 2b	Pearson Leary J, McNay E. Novel Roles for the Insulin-Regulated Glucose Transporter-4 in Hippocampally Dependent Memory. J Neurosci. 2016;36:11851-11864 pubmed
western blot; mouse; loading ...; fig 3d	Coleman S, Rebalka I, D Souza D, Deodhare N, Desjardins E, Hawke T. Myostatin inhibition therapy for insulin-deficient type 1 diabetes. Sci Rep. 2016;6:32495 pubmed publisher
	Varghese M, Niihori M, Eccles C, Kurdyukov S, James J, Rafikova O, et al. Antioxidant-Conjugated Peptide Attenuated Metabolic Reprogramming in Pulmonary Hypertension. Antioxidants (Basel). 2020;9: pubmed publisher
	Zhang Y, Xie L, Gunasekar S, Tong D, Mishra A, Gibson W, et al. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nat Cell Biol. 2017;19:504-517 pubmed publisher

product information

Catalog Number :

07-1404

Subcategory :

Cell Signaling

Product Name :

Anti-GLUT-4 Antibody, C-terminus 07-1404

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P14672

Host Name :

Rabbit

Antigen :

GLUT-4

Conjugate :

Affinity Purified

Product Description :

Anti-GLUT-4 Antibody, C-terminus 07-1404

Cross Reactivity :

Human;Mouse

Background :

The protein called GLUT-4, or more correctly Solute carrier family 2, facilitated glucose transporter member 4 and encoded by the human gene SLC2A4/GLUT4 is a primary insulin regulated facilitative glucose transporter found primarily in skeletal and cardiac muscle, as well as brown and white fat but is also expressed in other tissues such as brain. In the brain GLUT4 is found exclusively in neurons. GLUT-4 is facilitative because it is not always present on the cell plasma membrane. GLUT-4 only localizes to the plasma membrane upon insulin induction. GLUT-4 is localized to the perinuclear region in resting cells. Mutations in GLUT-4 are a cause of one form of non-insulin dependent diabetes mellitus. GLUT4 function as well as its transcriptional regulation is highly conserved throughout the vertebrate species.

ALT Names :

Solute carrier family 2, facilitated glucose transporter member 4;Glucose transporter type 4, insulin-responsive;GLUT-4

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human GLUT-4.

Specificity :

Glucose transporter 4 (GLUT-4) is a protein present in rat skeletal muscle, heart and adipose tissues. GLUT-4 is highly conserved between species, and the peptide sequence selected for production of this antibody is identical in rat, human (amino acids 498-510), and mouse. This antibody shows no cross-reactivity of HepG2 type transporter from rat brain or other glucose transporters.

Package Size :

100 μL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt