CDT1 Antibody | EMD Millipore 07-1383 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CDT1 Antibody

catalog :

07-1383

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 5	Ma X, Lin F, Wang Z, Hu M, Huang L, Meng T, et al. Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility. Mol Biol Cell. 2016;27:768-75 pubmed publisher

product information

Catalog Number :

07-1383

Subcategory :

Cell Signaling

Product Name :

Anti-CDT1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9H211

Host Name :

Rabbit

Antigen :

CDT1

Product Description :

Anti-CDT1 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

CDT1 (Chromatin Licensing and DNA replication Factor 1) is an essential component of the cell cycle machinery. It plays an important role in insuring that there is only one round of DNA replication per cell cycle. CDT1 is a known substrate of Cdk2 and Cdk4 (Liu, E. 2004). It is presented in G1 of the cell cycle and is degraded as cells enter S phase (Liu, E. 2004). In higher eukaryotes, CDT1 is known to interact with Geminin, a protein that is degraded during mitosis, that inhibits it. CDT1 is marked for degradation by two E3 ligases: SCF complex and the CUL4-DDB1 complex (Sansam, 2006).

ALT Names :

DNA replication factor ;Double parked homolog ;Double parked, Drosophila, homolog of 2 chromatin licensing and DNA replication factor 1

Immunogen :

Recombinant protein including amino acids 238-546 of human CDT1.

Specificity :

This antibody recognizes the Cdt1.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 2 years at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.