DAPK2 Antibody | EMD Millipore 07-1229 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

DAPK2 Antibody

catalog :

07-1229

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

07-1229

Subcategory :

Cell Signaling

Product Name :

Anti-DAPK2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9UIK4

Host Name :

Rabbit

Antigen :

DAPK2

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-DAPK2 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

Death Associated Protein Kinase (DAPK) is a Ca2+/Calmodulin-dependent, cytoskeletal associated protein kinase whose expression is implicated in the sensitivity of cells to apoptotic effects of TNFα and Interferon-γ. Deletion of the Calmodulin-binding domain results in a constitutively active mutant with a more potent cytotoxic effect. In contrast, the catalytically inactive mutant exerts a dominant negative effect, reducing cytotoxicity and protecting cells from Interferon-γ induced cell death. DAPK expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlate with high rates of metastasis.

ALT Names :

DAP kinase;DAP- kinase-related protein;Death-associated protein kinase

Immunogen :

Peptide corresponding to aa 356-370 (ARRKALHPRRRSSTS) of human DAPK2, which is identical to the sequence of mouse origin.

Specificity :

Detects a 42 kDa band by western blot, corresponding to DAPK2. Does not cross-react with DAPK1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 6 months at 2-8° C from date of receiept.