Sp3 Antibody | EMD Millipore 07-107 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Sp3 Antibody

catalog :

07-107

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation, EMSA

citations: 2

Published Application/Species/Sample/Dilution	Reference
EMSA; human; loading ...; fig 5d	Hu T, Zhu X, Pi W, Yu M, Shi H, Tuan D. Hypermethylated LTR retrotransposon exhibits enhancer activity. Epigenetics. 2017;12:226-237 pubmed publisher
EMSA; mouse; loading ...; fig 7c	McDonald E, Smith J, Cederberg R, White B. Divergent activity of the gonadotropin-releasing hormone receptor gene promoter among genetic lines of pigs is partially conferred by nuclear factor (NF)-B, specificity protein (SP)1-like and GATA-4 binding sites. Reprod Biol Endocrinol. 2016;14:36 pubmed publisher

product information

Catalog Number :

07-107

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Sp3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q02447

Host Name :

Rabbit

Antigen :

Sp3

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Sp3 Antibody

Cross Reactivity :

Human;Mouse;Rat;Rabbit

Background :

The sequence-specific transcription factor Sp3 binds GC and GT box sequences in the promoters of a variety of genes. The Sp3 transcription factor contains three zinc finger domains that determine sequence specificity of DNA binding. This transcription factor is thought to regulate nucleoside, nucleotide and nucleic acid metabolism and many other “housekeeping” genes. Sp3 can be modified by sumoylation by Ubc9 and has been shown to interact with other transcription factors and histonbe deacetylases. Sp3 has been reported to act as a transcriptional enhancer and repressor of Sp1 activity in a cell- and context-dependent manner.

Immunogen :

Fusion protein corresponding to amino acid residues 239-653 of human Sp3

Specificity :

Sp3 isoforms

Package Size :

200 µg

Uses :

Electrophoretic Mobility Shift Assay;Immunoprecipitation;Western Blotting

Storage :

2 years at -20°C