Upf1 Antibody | EMD Millipore 07-1014 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Upf1 Antibody

catalog :

07-1014

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, bovine

application :

western blot, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse; fig 4a western blot; mouse; fig 2c	Sanchez G, Bondy Chorney E, Laframboise J, Paris G, Didillon A, Jasmin B, et al. A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. Nucleic Acids Res. 2016;44:2661-76 pubmed publisher

product information

Catalog Number :

07-1014

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Upf1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q92900

Host Name :

Rabbit

Antigen :

Upf1

Conjugate :

Purified

Product Description :

Anti-Upf1 Antibody

Cross Reactivity :

Bovine;Human;Mouse;Rat;Canine

Background :

Upf1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. Upf1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.

ALT Names :

ATP-dependent helicase RENT1 ;Nonsense mRNA reducing factor 1;UP Frameshift 1;UPF1 regulator of nonsense transcripts homolog (yeast);Up-frameshift suppressor 1 homolog ;delta helicase ;regulator of nonsense transcripts 1;up-frameshift mutation 1 homolog ;yeast Upf1p homolog

Immunogen :

KLH-conjugated synthetic linear peptide corresponding to Upf1.

Specificity :

This antibody detects Upf1.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8ºC from date of receipt.