IKKα Antibody | EMD Millipore 07-1007 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

IKKα Antibody

catalog :

07-1007

quantity :

150 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dog, cow

application :

western blot, immunoprecipitation

product information

Catalog Number :

07-1007

Subcategory :

Inflammation & Immunology

Product Name :

Anti-IKKα Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O15111

Host Name :

Rabbit

Antigen :

IKKα

Conjugate :

Purified

Product Description :

Anti-IKKα Antibody

Cross Reactivity :

Human;Canine;Horse;Bovine;Rat;Mouse

Background :

The TNF and IL-1 signaling pathways activate the IκB kinases, IKKα (IKK1), IKKβ (IKK2). Phosphorylation of the IκB cytoplasmic inhibitors, IκBα, IκBβ and IκBγ by these kinases triggers proteolytic degradation and the release of NFκB/Rel proteins from the IκB inhibitors. This allows the NFκB proteins to enter the nucleus. A third member of the family, IKKε (IKKI), is not induced by TNF or IL-1. IKKε together with TANK-binding kinase-1 (TBK1), is essential for resistance to viral infection; either kinase can phosphorylate IRF3 and IRF7, leading to their nuclear translocation and induction of interferon and ISG56 gene expression.

ALT Names :

I kappa-B kinase alpha ;I-kappa-B kinase 1 ;I-kappa-B kinase-alpha ;IKK-a kinase ;IkB kinase alpha subunit ;IkappaB kinase ;Nuclear factor NF-kappa-B inhibitor kinase alpha;Nuclear factor NFkappaB inhibitor kinase alpha ;conserved helix-loop ubiquitous kinase ;conserved helix-loop-helix ubiquitous kinase

Immunogen :

KLH-conjugated linear peptide corresponding to IKKα.

Specificity :

This antibody recognizes IKKα.

Package Size :

150 µg

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable at 2-8°C for 1 year from date of receipt.