Mn-SOD Antibody | EMD Millipore 06-984 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Mn-SOD Antibody

catalog :

06-984

quantity :

200 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s7a	Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed publisher
immunohistochemistry - paraffin section; rat; loading ...; fig 1a, 2a, 3a immunoprecipitation; rat; 1:20; loading ...; fig 6a, 6c western blot; rat; 1:200; loading ...; fig 2d, 6a, 3c	Moya E, Arias P, Iturriaga R. Nitration of MnSOD in the Carotid Body and Adrenal Gland Induced by Chronic Intermittent Hypoxia. J Histochem Cytochem. 2018;66:753-765 pubmed publisher
western blot; rat; 1:1000; loading ...; fig 7a	Parajuli N, Shrum S, Tobacyk J, Harb A, Arthur J, Macmillan Crow L. Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins. PLoS ONE. 2017;12:e0185542 pubmed publisher
western blot; rat; loading ...; fig 1c	Himori K, Abe M, Tatebayashi D, Lee J, Westerblad H, Lanner J, et al. Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension. PLoS ONE. 2017;12:e0169146 pubmed publisher
western blot; human; fig 1e	Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher
western blot; mouse; loading ...; fig 5c	Li W, Jin D, Hata M, Takai S, Yamanishi K, Shen W, et al. Dysfunction of mitochondria and deformed gap junctions in the heart of IL-18-deficient mice. Am J Physiol Heart Circ Physiol. 2016;311:H313-25 pubmed publisher
	Henríquez Olguín C, Knudsen J, Raun S, Li Z, Dalbram E, Treebak J, et al. Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. Nat Commun. 2019;10:4623 pubmed publisher
	Kenny T, Craig A, Villanueva A, Germain D. Mitohormesis Primes Tumor Invasion and Metastasis. Cell Rep. 2019;27:2292-2303.e6 pubmed publisher
	Tian X, Wang F, Luo Y, Ma S, Zhang N, Sun Y, et al. Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation. Front Oncol. 2018;8:542 pubmed publisher
	Kauppila J, Bonekamp N, Mourier A, Isokallio M, Just A, Kauppila T, et al. Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res. 2018;46:6642-6669 pubmed publisher
	Kenny T, Hart P, Ragazzi M, Sersinghe M, Chipuk J, Sagar M, et al. Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis. Oncogene. 2017;36:4393-4404 pubmed publisher
	DellaValle B, Brix G, Brock B, Gejl M, Landau A, Møller A, et al. Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats. Front Pharmacol. 2016;7:433 pubmed
	Woo S, Min K, Seo B, Kwon T. YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-?B-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells. Oncotarget. 2016;7:61520-61532 pubmed publisher
	Kalef Ezra E, Kotzamani D, Zaganas I, Katrakili N, Plaitakis A, Tokatlidis K. Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence. Biochem J. 2016;473:2813-29 pubmed publisher
	Urasaki Y, Pizzorno G, Le T. Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice. PLoS ONE. 2016;11:e0146994 pubmed publisher

product information

Catalog Number :

06-984

Subcategory :

Neuroscience

Product Name :

Anti-Mn-SOD Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P04179

Host Name :

Rabbit

Antigen :

Mn-SOD

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Mn-SOD Antibody

Cross Reactivity :

Human;Rat;Mouse;Bovine

Background :

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn SOD/SOD1), mitochondrial manganese SOD (Mn SOD/SOD2) and extracellular Cu, Zn SOD (EC SOD/SOD3). The manganese containing 80 kDa tetrameric enzyme SOD2 is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain.

ALT Names :

Mn superoxide dismutase;indophenoloxidase B;manganese superoxide dismutase;manganese-containing superoxide dismutase;mangano-superoxide dismutase;superoxide dismutase 2, mitochondrial

Immunogen :

Recombinant human MnSOD (manganous superoxide dismutase).

Specificity :

Recognizes MnSOD, Mr 24 kDa.

Package Size :

200 μg

Uses :

Immunohistochemistry;Immunohistochemistry (Paraffin);Western Blotting

Storage :

Stable for 1 year at 2 to 8ºC from date of receipt.