hyperacetylated Histone H4 (Penta) Antibody | EMD Millipore 06-946 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

hyperacetylated Histone H4 (Penta) Antibody

catalog :

06-946

quantity :

200 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, chromatin immunoprecipitation

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:500; loading ...; fig s4b	Żylicz J, Bousard A, Zumer K, Dossin F, Mohammad E, da Rocha S, et al. The Implication of Early Chromatin Changes in X Chromosome Inactivation. Cell. 2019;176:182-197.e23 pubmed publisher
	Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
	Rollins M, Huard S, Morettin A, Takuski J, Pham T, Fullerton M, et al. Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. PLoS Genet. 2017;13:e1006626 pubmed publisher

product information

Catalog Number :

06-946

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-hyperacetylated Histone H4 (Penta) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P62805

Host Name :

Rabbit

Antigen :

hyperacetylated Histone H4 (Penta)

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-hyperacetylated Histone H4 (Penta) Antibody

Cross Reactivity :

Human;Tetrahymena;Eukaryote

Background :

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

ALT Names :

H4 histone family, member A;histone 1, H4a;histone cluster 1, H4a

Immunogen :

KLH-conjugated, synthetic peptide (AGGAcKGGAcKGGAcKGGAcKGGAcKGGC) related to amino acids 2 to 19 of Tetrahymena thermophila histone H4.

Specificity :

Recognizes hyperacetylated histone H4, Mr 10 kDa (SDS-PAGE); tri- and tetra-acetylated histone H4 on acid-urea gels. May cross-react with other acetylated proteins.

Package Size :

200 µL

Uses :

Immunocytochemistry;Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at -20°C from date of receipt. For maximum recovery of product, centrifuge the vial prior to removing the cap. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variabillity in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.