Estrogen Receptor α Antibody | EMD Millipore 06-935 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Estrogen Receptor α Antibody

catalog :

06-935

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, ChIP-Seq

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:10,000; loading ...; fig 1a	Tran M, Braz J, Hamel K, Kuhn J, Todd A, Basbaum A. Ablation of spinal cord estrogen receptor α-expressing interneurons reduces chemically induced modalities of pain and itch. J Comp Neurol. 2020;528:1629-1643 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:10,000; loading ...; fig 3d	Wang L, Vanacker C, Burger L, Barnes T, Shah Y, Myers M, et al. Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction. elife. 2019;8: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:6000; loading ...; fig 4a	Lischinsky J, Sokolowski K, Li P, Esumi S, Kamal Y, Goodrich M, et al. Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues. elife. 2017;6: pubmed publisher
immunohistochemistry - paraffin section; mouse; tbl 2	Luque R, Villa Osaba A, L LÃ³pez F, Pozo Salas A, SÃ¡nchez SÃ¡nchez R, Ortega Salas R, et al. Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode. Breast Cancer Res. 2016;18:29 pubmed publisher
ChIP-Seq; human; loading ...; fig 3f western blot; human; loading ...; fig 3c	Xue X, Yang Y, Zhang A, Fong K, Kim J, Song B, et al. LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer. Oncogene. 2016;35:2746-55 pubmed publisher
	Biehl M, Kaylan K, Thompson R, Gonzalez R, Weis K, Underhill G, et al. Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling. Dev Biol. 2018;442:87-100 pubmed publisher
	Farman H, Windahl S, Westberg L, Isaksson H, Egecioglu E, Schéle E, et al. Female Mice Lacking Estrogen Receptor-? in Hypothalamic Proopiomelanocortin (POMC) Neurons Display Enhanced Estrogenic Response on Cortical Bone Mass. Endocrinology. 2016;157:3242-52 pubmed publisher

product information

Catalog Number :

06-935

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Estrogen Receptor α Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P06211

Host Name :

Rabbit

Antigen :

Estrogen Receptor α

Conjugate :

Affinity Purified

Product Description :

Anti-Estrogen Receptor α Antibody

Cross Reactivity :

Human;Rat;Mouse

Background :

Estrogen Receptor alpha is a 65 kDa protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, Estrogen Receptor alpha can positively or negatively regulate gene transcription. Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role in regulating mammary gland growth and differentiation. Breast tumors that are ER positive may also show a more favorable response to anti-estrogen therapies.

ALT Names :

ER-alpha;Estradiol receptor;Nuclear receptor subfamily 3 group A member 1

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of rat Estrogen Receptor alpha.

Specificity :

This antibody recognizes the C-terminus of Estrogen Receptor alpha.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt