Histone H3 Antibody | EMD Millipore 06-755 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3 Antibody

catalog :

06-755

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 16

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; human; 1:500; loading ...; fig 6c	Chen Q, Kassab M, Dantzer F, Yu X. PARP2 mediates branched poly ADP-ribosylation in response to DNA damage. Nat Commun. 2018;9:3233 pubmed publisher
western blot; mouse; fig 6b	Lamonica J, Kwon D, Goffin D, Fenik P, Johnson B, Cui Y, et al. Elevating expression of MeCP2 T158M rescues DNA binding and Rett syndrome-like phenotypes. J Clin Invest. 2017;127:1889-1904 pubmed publisher
western blot; human; loading ...; fig s12	Ando T, Yamayoshi S, Tomita Y, Watanabe S, Watanabe T, Kawaoka Y. The host protein CLUH participates in the subnuclear transport of influenza virus ribonucleoprotein complexes. Nat Microbiol. 2016;1:16062 pubmed publisher
western blot; mouse; fig s9	Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher
	González Rico F, Vicente Garcia C, Fernandez A, Muñoz Santos D, Montoliu L, Morales Hernández A, et al. Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor. Epigenetics Chromatin. 2020;13:15 pubmed publisher
	Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, et al. The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019;28:698-711.e5 pubmed publisher
	Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo M, et al. β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
	Yao R, Wang Y, Han D, Ma Y, Ma M, Zhao Y, et al. Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration. Oncol Rep. 2018;40:3069-3077 pubmed publisher
	Wang B, Yang X, Wang Y, Xie Y, Zhou X. Tomato Yellow Leaf Curl Virus V2 Interacts with Host Histone Deacetylase 6 To Suppress Methylation-Mediated Transcriptional Gene Silencing in Plants. J Virol. 2018;92: pubmed publisher
	Han F, Miyagawa Y, Verlengia G, Ingusci S, Soukupova M, Simonato M, et al. Cellular Antisilencing Elements Support Transgene Expression from Herpes Simplex Virus Vectors in the Absence of Immediate Early Gene Expression. J Virol. 2018;92: pubmed publisher
	Chen L, Alexe G, Dharia N, Ross L, Iniguez A, Conway A, et al. CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2. J Clin Invest. 2018;128:446-462 pubmed publisher
	Li C, Zheng Z, Jiang J, Jiang W, Lee K, Berthiaume E, et al. Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3-Mediated Indian Hedgehog Signaling. Am J Pathol. 2018;188:392-403 pubmed publisher
	Grey W, Ivey A, Milne T, Haferlach T, Grimwade D, Uhlmann F, et al. The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability. Biochim Biophys Acta Mol Cell Res. 2018;1865:105-116 pubmed publisher
	Nguyen H, Dong J, Panchakshari R, Kumar V, Alt F, Bories J. Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination. Proc Natl Acad Sci U S A. 2017;114:E10560-E10567 pubmed publisher
	Guida N, Laudati G, Mascolo L, Cuomo O, Anzilotti S, Sirabella R, et al. MC1568 Inhibits Thimerosal-Induced Apoptotic Cell Death by Preventing HDAC4 Up-Regulation in Neuronal Cells and in Rat Prefrontal Cortex. Toxicol Sci. 2016;154:227-240 pubmed
	Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mol Cell Biol. 2016;36:2487-502 pubmed publisher

product information

Catalog Number :

06-755

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

Histone H3

Conjugate :

Affinity Purified

Product Description :

Anti-Histone H3 Antibody

Cross Reactivity :

Human;Rat;Mouse

Background :

Histone H3, also known as Histone H3.1t, H3/t, H3t, or H3/g, and encoded by the gene HIST3H3/H3Ft, is one of the core components of the nucleosome. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The octamer wraps approximately 147 bp of DNA. A classic nuclear marker, new expression is seen during S phase of the cell cycle. Histone H3 is often acetylated and or methylated multiple times. Changes in methylation or acetylation state of histone H3 together with similar modification on the sister histones is one key aspect of epigenetic gene expression and regulation.

ALT Names :

Histone H3.1t;H3/t;H3t;H3/g

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of human Histone H3.

Specificity :

This antibody recognizes Histone H3 at the N-terminus.

Package Size :

100 µg

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt