β-Catenin Antibody | EMD Millipore 06-734 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

β-Catenin Antibody

catalog :

06-734

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:200; fig st1	Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
	Wu Z, Sun L, Liu G, Liu H, Liu H, Yu Z, et al. Hair follicle development and related gene and protein expression of skins in Rex rabbits during the first 8 weeks of life. Asian-Australas J Anim Sci. 2019;32:477-484 pubmed publisher
	Renner G, Noulet F, Mercier M, Choulier L, Etienne Selloum N, Gies J, et al. Expression/activation of ?5?1 integrin is linked to the ?-catenin signaling pathway to drive migration in glioma cells. Oncotarget. 2016;7:62194-62207 pubmed publisher
	Widlund H, Horstmann M, Price E, Cui J, Lessnick S, Wu M, et al. Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. J Cell Biol. 2002;158:1079-87 pubmed

product information

Catalog Number :

06-734

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-β-Catenin Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P35222

Host Name :

Rabbit

Antigen :

β-Catenin

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-β-Catenin Antibody

Cross Reactivity :

Human;Rat;Mouse;Rabbit;Bovine

Background :

β-catenin plays a central role in cell adhesion, bridging between cadherins and actin cytoskeleton. These activities are regulated through its differential interaction with several molecular partners, including cell-cell adherens junction (AJ) molecules, components of its degradation complex, and transcription factors. β-Catenin is composed of three domains: a central armadillo repeat domain and two N- and C-terminal tails. β-catenin can be phosphorylated by serine-threonine kinase, such as GSK-3. The phosphorylated β-catenin affects the protein association of β-catenin to E-cadherin and α-cateinin that occurs in the cell. This process can be reversed by de-phosphorylation of β-catenin.

ALT Names :

catenin (cadherin-associated protein), beta 1 (88kD);catenin (cadherin-associated protein), beta 1 (88kDa);catenin (cadherin-associated protein), beta 1, 88kDa

Immunogen :

KLH-conjugated, synthetic peptide (CGG-SYLDSGIHSGATTTAPSLSGK) corresponding to the consensus GSK3 phosphorylation site of human β -Catenin (amino acids 29-49).

Specificity :

Recognizes β-Catenin, Mr 92 kDa.

Package Size :

200 µg

Uses :

Immunocytochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt. Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution.