acetyl-Histone H4 Antibody | EMD Millipore 06-598 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

acetyl-Histone H4 Antibody

catalog :

06-598

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, Xenopus laevis

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 17

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; Xenopus laevis; fig 4	Tamaoki K, Okada R, Ishihara A, Shiojiri N, Mochizuki K, Goda T, et al. Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis. Cell Biosci. 2016;6:2 pubmed publisher
western blot; human; fig 1	Kelkar M, Senthilkumar K, Jadhav S, Gupta S, Ahn B, De A. Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation. Sci Rep. 2016;6:19341 pubmed publisher
	Ma H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019;5:eaaw0683 pubmed publisher
	Huai W, Liu X, Wang C, Zhang Y, Chen X, Chen X, et al. KAT8 selectively inhibits antiviral immunity by acetylating IRF3. J Exp Med. 2019;216:772-785 pubmed publisher
	Basilicata M, Bruel A, Semplicio G, Valsecchi C, Aktas T, Duffourd Y, et al. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nat Genet. 2018;50:1442-1451 pubmed publisher
	Valsecchi C, Basilicata M, Semplicio G, Georgiev P, Gutierrez N, Akhtar A. Facultative dosage compensation of developmental genes on autosomes in Drosophila and mouse embryonic stem cells. Nat Commun. 2018;9:3626 pubmed publisher
	Lee B, Choi A, Kim J, Jun Y, Woo H, Ha S, et al. Rpd3L HDAC links H3K4me3 to transcriptional repression memory. Nucleic Acids Res. 2018;46:8261-8274 pubmed publisher
	Joo Y, Ficarro S, Soares L, Chun Y, Marto J, Buratowski S. Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation. Genes Dev. 2017;: pubmed publisher
	Acharya D, Hainer S, Yoon Y, Wang F, Bach I, Rivera PÃ©rez J, et al. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017;19:671-679 pubmed publisher
	Nagaki K, Yamaji N, Murata M. ePro-ClearSee: a simple immunohistochemical method that does not require sectioning of plant samples. Sci Rep. 2017;7:42203 pubmed publisher
	Bulusu V, Tumanov S, Michalopoulou E, van den Broek N, Mackay G, Nixon C, et al. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation. Cell Rep. 2017;18:647-658 pubmed publisher
	Xie J, Jenull S, Tscherner M, Kuchler K. The Paralogous Histone Deacetylases Rpd3 and Rpd31 Play Opposing Roles in Regulating the White-Opaque Switch in the Fungal Pathogen Candida albicans. MBio. 2016;7: pubmed publisher
	Cuella Martin R, Oliveira C, Lockstone H, Snellenberg S, Grolmusova N, Chapman J. 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms. Mol Cell. 2016;64:51-64 pubmed publisher
	Wei Y, Liu J, Villaescusa J, Aberg E, Brene S, Wegener G, et al. Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression. Transl Psychiatry. 2016;6:e869 pubmed publisher
	Lu Y, Liu Y, Liao S, Tu W, Shen Y, Yan Y, et al. Epigenetic modifications promote the expression of the orphan nuclear receptor NR0B1 in human lung adenocarcinoma cells. Oncotarget. 2016;7:43162-43176 pubmed publisher
	Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, et al. Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon. Mol Cell Biol. 2016;36:1297-309 pubmed publisher
	Clifford R, John A, Brightling C, Knox A. Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma. J Immunol. 2012;189:819-31 pubmed publisher

product information

Catalog Number :

06-598

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-acetyl-Histone H4 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P62805

Host Name :

Rabbit

Antigen :

acetyl-Histone H4

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-acetyl-Histone H4 Antibody

Cross Reactivity :

Tetrahymena;Human

Background :

Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

ALT Names :

H4 histone family, member A;histone 1, H4a;histone cluster 1, H4a

Immunogen :

KLH-conjugated peptide corresponding to amino acids 2-19 of Tetrahymena histone H4 (AGG(Ac)KGG(Ac)KGMG(Ac)KVGA(Ac)KRHS-C), acetylated on lysines 5,8,12 and 16.

Specificity :

Recognizes acetylated histone H4. Cross-reacts with acetylated histone H2B from Tetrahymena and weakly cross-reacts with acetylated histone H2B from HeLa cells. May crossreact with other acetylated proteins.

Package Size :

200 µg

Uses :

Immunocytochemistry;Immunoprecipitation;Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

1 year at -20°C from date of shipment. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.