Kip1 (p27) Antibody | EMD Millipore 06-445 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Kip1 (p27) Antibody

catalog :

06-445

quantity :

200 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4a	Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019;19:898 pubmed publisher

product information

Catalog Number :

06-445

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Kip1 (p27) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P46527

Host Name :

Rabbit

Antigen :

Kip1 (p27)

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Kip1 (p27) Antibody

Cross Reactivity :

Human;Rat;Rabbit

Background :

p27(Kip1) is a cyclin-dependent kinase inhibitor involved in G1 arrest. p27(Kip1) binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. p27(Kip1) is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27(Kip1); while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm.

Immunogen :

An 18 amino acid synthetic peptide ([C]GSVEQTPKKPGLRRRQT) linked to KLH was used to immunize rabbits

Specificity :

Recognizes Kip1.

Package Size :

200 μg

Uses :

Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.