Myc Antibody | EMD Millipore 06-340 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Myc Antibody

catalog :

06-340

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section, immunohistochemistry knockout validation

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; 1:100; fig 4 immunohistochemistry - frozen section; mouse; 1:100; fig s3	Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed publisher
	Krzysiak T, Thomas L, Choi Y, Auclair S, Qian Y, Luan S, et al. An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity. Mol Cell. 2018;72:985-998.e7 pubmed publisher
	Sawaya A, Pastar I, Stojadinovic O, Lazovic S, Davis S, Gil J, et al. Topical mevastatin promotes wound healing by inhibiting the transcription factor c-Myc via the glucocorticoid receptor and the long non-coding RNA Gas5. J Biol Chem. 2018;293:1439-1449 pubmed publisher
	Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed publisher
	Wang J, Xu Y, Li L, Wang L, Yao R, Sun Q, et al. FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer. Cancer Med. 2017;6:275-287 pubmed publisher

product information

Catalog Number :

06-340

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Myc Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P01106

Host Name :

Rabbit

Antigen :

Myc

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Myc Antibody

Cross Reactivity :

Human;Mouse;Avian;Xenopus

Background :

c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression.

ALT Names :

Transcription factor p64;avian myelocytomatosis viral oncogene homolog;myc proto-oncogene protein;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog (avian)

Immunogen :

Bacterially expressed fusion-protein corresponding to the full-length human Myc.

Specificity :

Recognizes Myc isoforms Mr 50-67kDa.

Package Size :

100 µg

Uses :

Immunocytochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.