JAK2 Antibody | EMD Millipore 06-255 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

JAK2 Antibody

catalog :

06-255

quantity :

150 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunoprecipitation

citations: 1

Reference
Akiyama H, Umezawa Y, Watanabe D, Okada K, Ishida S, Nogami A, et al. Inhibition of USP9X Downregulates JAK2-V617F and Induces Apoptosis Synergistically with BH3 Mimetics Preferentially in Ruxolitinib-Persistent JAK2-V617F-Positive Leukemic Cells. Cancers (Basel). 2020;12: pubmed publisher

product information

Catalog Number :

06-255

Subcategory :

Cell Signaling

Product Name :

Anti-JAK2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O60674

Host Name :

Rabbit

Antigen :

JAK2

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-JAK2 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

The Janus family of tyrosine kinases (JAK) includes JAK1, JAK2, JAK3 and Tyk2. This family associates with a variety of cytokine receptors and is activated by ligand binding. Upon ligand binding to cytokine receptors, JAKs phosphorylate themselves and their associated receptors. This provides multiple binding sites for signaling proteins containing SH2 or other phospho-tyrosine-binding domains, including STATs, Shc, insulin receptor substrates and FAK.

Immunogen :

peptide corresponding to residues 758-776 of murine JAK2

Specificity :

Recognizes murine, human, and rat JAK2, Mr 130kDa. Additional bands may be detected in some lysates.

Package Size :

150 μL

Uses :

Immunoprecipitation;Western Blotting

Storage :

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.