Cyclin A Antibody | EMD Millipore 06-138 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cyclin A Antibody

catalog :

06-138

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

06-138

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Cyclin A Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P20248

Host Name :

Rabbit

Antigen :

Cyclin A

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Cyclin A Antibody

Cross Reactivity :

Human;Mouse;Rat;Sheep

Background :

The cell cycle is regulated by the interplay of many molecules. Key among these are the cyclins which are expressed and then degraded in a concerted fashion to drive the stages of the cell cycle. Cyclins combine with cyclin dependent kinases (cdks) to form activated kinases that phosphorylate targets leading to cell cycle regulation. A breakdown in the regulation of this cycle can lead to out of control growth and contribute to tumor formation. Defects in many of the molecules that regulate the cell cycle have been implicated in cancer. Cyclin A is a member of the Cyclin A family that can bind and activate Cdc2 and Cdk2 and is involved in the control of mitosis and S phase. During S phase, cyclin A forms a complex with Cdk2, the pRB-related protein p107 and E2F.

Immunogen :

peptide corresponding amino acid residues 417-432 (C-KHGVSLLNPPETL-N-L)

Specificity :

p58cyclin A; does not cross-react with cyclin B or cyclin D2, or 3

Package Size :

200 µg

Uses :

Immunoprecipitation;Western Blotting;Immunocytochemistry

Storage :

2 years at -20°C