Histone H2A.Bbd Antibody | EMD Millipore 06-1319 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H2A.Bbd Antibody

catalog :

06-1319

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1d	Leung J, Makharashvili N, Agarwal P, Chiu L, Pourpre R, Cammarata M, et al. ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes Dev. 2017;31:260-274 pubmed publisher

product information

Catalog Number :

06-1319

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H2A.Bbd Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P0C5Y9

Host Name :

Rabbit

Antigen :

Histone H2A.Bbd

Conjugate :

Affinity Purified

Product Description :

Anti-Histone H2A.Bbd Antibody

Cross Reactivity :

Human;Mouse

Background :

Histone H2A.Bbd (Barr body-deficient), also known as histone H2A-Bbd type 1, is an atypical histone variant. This histone variant associates with H2B and replaces histone H2A in the nucleosome. In contrast to other H2A histones, this variant lacks conserved residues that are targets of post-translational modifications. Consequently this H2A.Bbd variant is about 15 amino acids shorter and only 48% similar to the canonical H2A. The major differences between the two are found in the docking domain that links H2A -H2B to the H3-H4 tetramer. Nucleosomes containing this histone adopt a more relaxed structure and protect ~118 base pairs of DNA instead of the 147 base pairs found in classical nucleosomes. This variant histone is associated with active X chromosomes and autosomes, and is typically absent from inactive X chromosomes.

ALT Names :

H2A histone family, member B1;H2A Barr body-deficient;histone H2A-Bbd type 1

Immunogen :

KLH-conjugated linear peptide corresponding to human Histone H2A.Bbd.

Specificity :

This antibody recognizes Histone H2A.Bbd.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt