U1-70K Antibody | EMD Millipore 06-1297 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

U1-70K Antibody

catalog :

06-1297

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; rat; 1:100; fig 7	Llorian M, Gooding C, Bellora N, Hallegger M, Buckroyd A, Wang X, et al. The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. Nucleic Acids Res. 2016;44:8933-8950 pubmed
	Mitra M, Johnson E, Swamy V, Nersesian L, Corney D, Robinson D, et al. Alternative polyadenylation factors link cell cycle to migration. Genome Biol. 2018;19:176 pubmed publisher

product information

Catalog Number :

06-1297

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-U1-70K Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P08621

Host Name :

Rabbit

Antigen :

U1-70K

Conjugate :

Purified

Product Description :

Anti-U1-70K Antibody

Cross Reactivity :

Human;Mouse

Background :

U1 small nuclear ribonucleoprotein 70 kDa (U1-70K) is one of three specific proteins found within the U1 snRNP core, which includes at least seven core proteins found in all U snRNPs and three specific proteins; U1-70K, U1-A, and U1-C. U1-70K is involved in mediating pre-mRNA splicing through binding the loop I region of U1-snRNA with its RPM (RNA recognition motif) binding domain. In addition, its RNA binding domain, U1-70K also contains two argine-rich regions, accented with acidic or serine residues, that is thought to have trans-acting functions. Alternative splicing results in 4 known isoforms. Truncated forms of U1-70K are unable to bind RNA.

ALT Names :

small nuclear ribonucleoprotein 70kDa (U1);U1 small nuclear ribonucleoprotein 70 kDa;small nuclear ribonucleoprotein 70kDa (RNP antigen);U1 snRNP 70 kDa

Immunogen :

Recombinant protein corresponding to C-terminal domain of human U1-70K.

Specificity :

This antibody recognizes U1-70K.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt