Cep63 Antibody | EMD Millipore 06-1292 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cep63 Antibody

catalog :

06-1292

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:500; loading ...; fig s8e	Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
immunohistochemistry; mouse; 1:200; loading ...; fig 2a western blot; mouse; 1:200; loading ...; fig 3I	Watanabe Y, Honda S, Konishi A, Arakawa S, Murohashi M, Yamaguchi H, et al. Autophagy controls centrosome number by degrading Cep63. Nat Commun. 2016;7:13508 pubmed publisher

product information

Catalog Number :

06-1292

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Cep63 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96MT8

Host Name :

Rabbit

Antigen :

Cep63

Conjugate :

Affinity Purified

Product Description :

Anti-Cep63 Antibody

Cross Reactivity :

Human;Mouse

Background :

Centrosomal protein 63 (Cep63) serves an ATM and ATR substrate for spindle assembly activation following chromosomal breakage. It is shown that inactivation of the CEP63 gene in avian DT40 cells impairs spindle assembly and prevents ATM- and ATR-dependent effects on mitosis. Cep63 is also reported to bind to and recruit Cdk1 to centrosomes and is thought to be involved the regulation mitotoic entry, centrosome amplification, and genome maintentance.

ALT Names :

Centrosomal protein of 63 kDa

Immunogen :

Recombinant protein corresponding to human Cep63.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt