TLR2 Antibody | EMD Millipore 06-1119 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TLR2 Antibody

catalog :

06-1119

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chimpanzee

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Wang Y, Li Y, Shen Q, Li X, Lu J, Li X, et al. Valsartan blocked alcohol-induced, Toll-like receptor 2 signaling-mediated inflammation in human vascular endothelial cells. Alcohol Clin Exp Res. 2014;38:2529-40 pubmed publisher

product information

Catalog Number :

06-1119

Subcategory :

Inflammation & Immunology

Product Name :

Anti-TLR2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O60603

Host Name :

Rabbit

Antigen :

TLR2

Conjugate :

Affinity Purified

Product Description :

Anti-TLR2 Antibody

Cross Reactivity :

Mouse;Human;Chimpanzee;Rhesus Macaque

Background :

Toll-like receptor 2 (TLR2) is a single-pass type I membrane protein belonging to the Toll-like receptor family and is comprised of 14 LRR repeats and a single TIR domain. TLR2 interacts with LY96 or TLR1 to regulate innate immune response to bacterial lipoproteins and other components of the microbial cell wall. It induces the activation of NFκB, inflammatory response and cytokine secretion through interactions with MYD88 and TRAF6. It may also function as a promoter for apoptosis. High expression of TLR2 has been reported in blood leukocytes, specifically in bone marrow, lymph node, monocytes and spleen. It has also been observed in fetal liver and lung tissues. Modifications in gene expression have been implicated in an increased susceptibility to leprosy.

ALT Names :

toll-like receptor 2;Toll/interleukin-1 receptor-like protein 4;toll/interleukin 1 receptor-like 4;CD282 antigen

Immunogen :

KLH-conjugated linear peptide corresponding to the extracellular domain of human TLR2.

Specificity :

This antibody recognizes the extracellular domain of TLR2.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt