P/CAF Antibody | EMD Millipore 06-1104 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

P/CAF Antibody

catalog :

06-1104

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chimpanzee

application :

western blot

product information

Catalog Number :

06-1104

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-P/CAF Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q92831

Host Name :

Rabbit

Antigen :

P/CAF

Conjugate :

Affinity Purified

Product Description :

Anti-P/CAF Antibody

Cross Reactivity :

Human;Mouse;Rat;Chimpanzee

Background :

P/CAF(sometimes called KAT2B) is a transcription cofactor with a histone acetyltransferase (HAT) activity. Consistent with this protein playing a direct role in transcriptional regulation, P/CAF can acetylate core histones H3 and H4, chromatin proteins HMG17 and HMG I(Y), as well as human immunodeficiency virus Tat, transcription factor MyoD, and general transcription factors TFIIE and TFIIF. A role for P/CAF in cell growth and differentiation is suggested by its interaction in vivo and in vitro with p300/CBP, two large nuclear proteins that bind to sequence-specific factors involved in cell growth/differentiation. A role for P/CAF in cell division is also suggested by data showing that this protein competes with E1A for binding sites in p300/CBP to counteract E1A's mitogenic activity.

ALT Names :

CREBBP-associated factor;Histone acetylase PCAF;K(lysine) acetyltransferase 2B;P300/CBP-associated factor;Histone acetyltransferase KAT2B

Immunogen :

KLH-conjugated linear peptide corresponding to the internal domain of human P/CAF.

Specificity :

This antibody recognizes the internal domain of P/CAF.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt